KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPHS1
All Species:
14.85
Human Site:
Y1114
Identified Species:
36.3
UniProt:
O60500
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60500
NP_004637.1
1241
134742
Y1114
E
D
R
V
R
N
E
Y
E
E
S
Q
W
T
G
Chimpanzee
Pan troglodytes
XP_524228
1241
134508
Y1114
E
D
R
V
R
N
E
Y
E
E
S
Q
W
T
G
Rhesus Macaque
Macaca mulatta
XP_001112314
1052
113512
D929
A
T
N
P
L
G
S
D
Q
T
N
I
Q
L
V
Dog
Lupus familis
XP_541685
1242
135134
Y1114
E
D
R
V
R
N
E
Y
E
D
S
R
W
T
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZS7
1242
134872
Y1114
E
D
R
I
R
N
E
Y
E
E
S
Q
W
T
G
Rat
Rattus norvegicus
Q9R044
1234
134286
N1107
G
S
E
D
R
I
R
N
E
Y
E
E
S
Q
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001035777
1242
137333
A1093
S
E
E
Q
R
S
T
A
S
S
S
T
R
Y
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q08180
764
82987
Q641
T
I
M
Q
N
N
H
Q
N
Q
L
Q
L
Q
Q
Honey Bee
Apis mellifera
XP_624127
1307
143527
Y1173
L
S
V
S
K
S
S
Y
I
G
N
P
S
P
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796903
1010
110769
D887
R
R
Y
D
D
Y
S
D
G
R
S
E
S
Y
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
80.9
87
N.A.
82.5
81.8
N.A.
N.A.
N.A.
N.A.
38.8
N.A.
20.9
26.9
N.A.
21.1
Protein Similarity:
100
99.5
83
92.6
N.A.
89.6
89.3
N.A.
N.A.
N.A.
N.A.
54.8
N.A.
33.6
42.9
N.A.
35.9
P-Site Identity:
100
100
0
86.6
N.A.
93.3
13.3
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
13.3
6.6
N.A.
6.6
P-Site Similarity:
100
100
13.3
100
N.A.
100
20
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
20
26.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
40
0
20
10
0
0
20
0
10
0
0
0
0
10
% D
% Glu:
40
10
20
0
0
0
40
0
50
30
10
20
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
10
0
0
10
10
0
0
0
0
40
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
10
0
10
0
0
10
0
0
10
0
0
0
% I
% Lys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
0
0
10
0
0
0
0
0
10
0
10
10
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
10
50
0
10
10
0
20
0
0
0
0
% N
% Pro:
0
0
0
10
0
0
0
0
0
0
0
10
0
10
0
% P
% Gln:
0
0
0
20
0
0
0
10
10
10
0
40
10
20
10
% Q
% Arg:
10
10
40
0
60
0
10
0
0
10
0
10
10
0
0
% R
% Ser:
10
20
0
10
0
20
30
0
10
10
60
0
30
0
0
% S
% Thr:
10
10
0
0
0
0
10
0
0
10
0
10
0
40
0
% T
% Val:
0
0
10
30
0
0
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
40
0
10
% W
% Tyr:
0
0
10
0
0
10
0
50
0
10
0
0
0
20
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _